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chronic diseases

IFC Statement on Advanced Glycation End Products

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Infant formula manufacturers continually work to ensure their products are safe and of the highest quality. When questions arise about the presence of a substance that commonly occurs during the heating and processing of food, such as advanced glycation end products (AGEs), these inquiries are taken very seriously.

All infant formulas are regulated by the US Food and Drug Administration. Neither the US FDA nor other regulatory/safety authorities have raised any concern about AGEs in infant formulas.

IFC Response to the Centers for Disease Control and Prevention's 2011 Vital Signs Report

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International Formula Council* (IFC) supports breastfeeding as the ideal choice for infant feeding. IFC also supports the right of parents to choose the feeding option for their baby that best fits their individual family situation.  For those mothers who cannot or choose not to breastfeed, infant formula is the only safe, nutritious, and recommended alternative.

BPA and the Developmental of Experimental Asthma in Mice

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A study published in the February, 2009 edition of Environmental Health Perspectives suggested that perinatal exposure to BPA promotes the development of experimental asthma in a mice model, susceptible of asthma.* The researchers exposed fetal and neonatal mice to BPA via maternal loading and assessed pups’ response to allergic sensitization and bronchial challenge. 

 
The BPA e

Study Linking BPA to Heart Disease Has Limitations

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A study in the January 2010 edition of Plos One, an online journal, titled, “Association of urinary bisphenol A concentration with heart disease: evidence from NHANES 2003/06” by Melzer et al.reports a statistical association between higher BPA levels and increased incidence of heart disease in the 2005-2006 National Health and Nutrition Examination Survey (NHANES) population.1 The authors conclude that “chance is an implausible explanation for the BPA association with heart disease.”  This report echoes findings published in 2008 in the Journal of the American Association (

Recommendations for Infant Feeding Research

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BPA and Breast Cancer

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IFC Evaluation of Study on Bisphenol A and Chemoresistance in Breast Cancer Cells

A study published in the October 2008 edition of Environmental Health Perspectives titled, “Bisphenol A at Low Nanomolar Doses Confers Chemoresistance in Estrogen Receptor Alpha Positive and Negative Breast Cancer Cells”1 found that 24 hour pretreatment of cells with free Bisphenol A (BPA) increased the chemoresistance of two breast cancer cell lines in vitro.  This study, however, has some major limitations which reduce the applicability of its findings.

The study was

Urinary BPA Concentrations and Chronic Diseases

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IFC Comments on a Recent Study that Finds Association with Urinary Bisphenol A Concentration and Chronic Diseases

A study published in the September 17, 2008 edition of the Journal of the American Medical Association (JAMA) showed a relationship between increasing urinary bisphenol A (BPA) concentration and the prevalence of self-reported chronic disease, including diabetes and cardiovascular disease.

Infant Feeding and Chronic Diseases

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IFC Statement of Facts Concerning Disease Claims Related to Infant Feeding

The International Formula Council (IFC)* and each of its members support breastfeeding and the American Academy of Pediatrics’ (AAP) position that breastfeeding is best, and that it offers specific child and maternal benefits. There is some evidence that breastfeeding is associated with a reduction in common acute childhood illnesses; however, it is not conclusive that breast milk is a direct cause of this reduction.